Today I'm going to talk about a very interesting paper (scientific article) that I read not so long ago, as part of an evaluation activity of an elective class called "new nano and micrometric size vehicles for biological applications" and I will try my best to summarize the paper as much simple as I can.
So the title of the paper is "Exosome-mimetic nanoplatforms (EMNs) for targeted cancer drug delivery" and all the investigation developed in it was aimed to solve a big problem of anticancer therapies: the non-selective reaching of the drugs to tumoral tissues.
Some kinds of cells are capable of secreting extracellular vesicles and one type of these vesicles of a nanometric size is called exosomes. What is important about these exosomes is that someones had tumor-homing properties and can be loaded with anticancer drugs, these two properties made them a pretty valuable technology to develop anticancer drugs but unfortunately, they are not exempt of safety problems (adverse effects) and bad production yields.
So the proposal of the scientists was to develop a platform that was pretty similar to exosomes but safer and easier to produce, using lipids and proteins that are present in exosomes. And to summarize, they managed to develop this technology and called it "Exosome-mimetic nanoplatforms". Of course this is not a reality in anticancer medicine yet, but it is an important advance in the nanomedicine field and who knows, maybe in a couple of years we'll see this technology applied.
Link to the article: https://doi.org/10.1186/s12951-019-0517-8
No hay comentarios:
Publicar un comentario